卢华定,男,主任医师,副教授,博士研究生,博士研究生导师,广东省人体生物组织工程学会常务理事兼副秘书长,广东省医学会关节外科青年委员、广东省医学会骨质疏松分会基础学组委员、广东省健康管理协会委员。从事骨科临床工作和研究20多年,获医学博士学位,曾去德国Ludiwigshafen 骨科创伤中心进修,获 AO Fellowship 证书。对各种骨关节创伤、关节退行性病变、股骨头坏死,骨肿瘤、慢性骨髓炎、肢体畸形矫形及老年性骨质疏松症等积累了丰富的临床经验。擅长髋、膝、肩关节置换手术;股骨头坏死的诊治;四肢及骨盆的严重骨与关节损伤、髋、膝、踝关节周围骨折的手术治疗;应用关节镜治疗各种关节疾患及关节运动创伤,对肢体畸形;慢性骨髓炎;良、恶性肿瘤等的诊治也有丰富的经验,对老年骨质疏松症的诊治亦有深入的研究。发表SCI收录论著10余篇,在国家核心期刊发表论文50余篇,主持3项国家自然科学基金、5项广东省级基金等课题的研究,并参加国家 863计划、广东省科技厅重点攻关课题研究。
论著:(*为通讯作者)
1)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. PGC-1α regulates the expression and activity of IRF-1. IUBMB Life. 2015 Apr 15. doi: 10.1002/iub.1369. [Epub ahead of print] SCI收录 IF: 2.755
2)Lu H*, Zhu L, Lian L, Chen M, Shi D, Wang K. Genetic variations in the PRKCG gene and osteosarcoma risk in a Chinese population: a case-control study. Tumour Biol. 2015 Feb 9. [Epub ahead of print] SCI收录 IF: 2.84
3)Lu H*, Zeng C, Zhao H, Lian L, Dai Y. Glatiramer acetate inhibits degradation of collagen II by suppressing the activity of interferon regulatory factor-1. Biochem Biophys Res Commun. 2014; 448(3): 323-328. SCI收录 IF: 2.281
4)Lu H*, Dai Y, Lv L, Zhao H. Chitosan-graft-polyethylenimine/DNA nanoparticles as novel non-viral gene delivery vectors targeting osteoarthritis. PLoS One. 2014; 9(1): e84703. SCI收录 IF: 3.534
5)Lu H*, Hou G, Zhang Y, Dai Y, Zhao H. c-Jun transactivates Puma gene expression to promote osteoarthritis. Mol Med Rep. 2014; 9(5):1606-1612. SCI收录 IF: 1.484
6)Hou G, Lu HD*, Chen MJ, Yao H, Zhao HQ. Oxidative Stress Participates in Age-related changes in Rat Lumbar Intervertebral Discs. Arch Gerontol Geriatr. 2014; 59: 665-669. SCI收录 IF: 1.525
7)Lu HD*, Lian LY, Shi DH, Zhao HQ, Dai YH. Hepcidin Promotes Osteogenic Differentiation through BMP2/SMAD and MAPK/P38 Signaling pathways in Mesenchymal stem cells. Mol Med Rep. 2015; 11: 143-150. SCI收录 IF: 1.484
8)Lu HD*, Zhao HQ, Wang K, Lv LL. Novel hyaluronic acid-chitosan nanoparticles as non-viral gene delivery vectors targeting osteoarthritis. Int ...
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